Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 4/20 | 0.39 |
| ▸ | KLK14 | Q9P0G3 | 4/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725540 | 0.84 | ENPP1 (0.48) | ENPP1ALDH1A1PDE10AMAPK1PDE3A | |
| SCHEMBL7164352 | 0.82 | ENPP1 (0.56) | ENPP1ALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL27882455 | 0.81 | ENPP1 (0.55) | ENPP1ALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL15819368 | 0.74 | ENPP1 (0.51) | ENPP1ALDH1A1PDE10APDE4AMAPK1 | |
| SCHEMBL29589930 | 0.74 | ENPP1 (0.51) | ENPP1ALDH1A1PDE10APDE4AMAPK1 | |
| SCHEMBL21642460 | 0.74 | ENPP1 (0.53) | ENPP1ALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL1013257 | 0.73 | ENPP1 (0.88) | ENPP1ALDH1A1FBP1EGFR | |
| SCHEMBL27248843 | 0.73 | ENPP1 (0.47) | ENPP1ALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL15519916 | 0.72 | ENPP1 (0.60) | ENPP1ALDH1A1KLK7KLK14KLK5 | |
| SCHEMBL8857662 | 0.72 | NTSR1 (0.51) | ENPP1ALDH1A1PDE10AMAPK1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | BAUER PAUL H (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | FBP1, HK1, G6PC1 | ENPP1 171/4885ALDH1A1 1023/4885KLK7 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.