Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.60 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945814 | 0.79 | PIK3CD (0.75) | PIK3CDASH1LKDRPIK3CBIMPDH2 | |
| SCHEMBL26259994 | 0.79 | CYP2A6 (0.52) | PIK3CDKDRPIK3CBIMPDH2CYP2E1 | |
| SCHEMBL20561837 | 0.77 | KDR (0.71) | ASH1LKDRIMPDH2CDK8 | |
| SCHEMBL20540332 | 0.77 | PIK3CD (0.64) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL2193011 | 0.76 | PIK3CD (0.70) | PIK3CDASH1LKDRPIK3CBIMPDH2 | |
| SCHEMBL29712113 | 0.76 | PIK3CD (0.70) | PIK3CDASH1LKDRPIK3CBIMPDH2 | |
| SCHEMBL5831286 | 0.75 | PIK3CD (1.00) | PIK3CDASH1LKDRPIK3CBIMPDH2 | |
| SCHEMBL31675815 | 0.75 | PIK3CD (1.00) | PIK3CDASH1LKDRPIK3CBIMPDH2 | |
| SCHEMBL9212052 | 0.75 | IMPDH2 (0.38) | KDRIMPDH2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL27725234 | 0.73 | PIK3CD (0.66) | PIK3CDASH1LKDRPIK3CBIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | PIK3CD 3331/4885ASH1L 3744/4885KDR 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.