Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26259994 | 0.78 | CYP2A6 (0.52) | IMPDH2CYP2A6CYP2B6CYP2E1KDR | |
| SCHEMBL9739475 | 0.77 | METAP2 (0.50) | CYP2A6KDR | |
| SCHEMBL7089571 | 0.75 | PIK3CD (0.60) | IMPDH2CYP2A6CYP2B6CYP2E1KDR | |
| SCHEMBL26259978 | 0.69 | CYP2A6 (0.58) | IMPDH2CYP2A6CYP2B6CYP2E1KDR | |
| SCHEMBL31378184 | 0.69 | NQO2 (0.53) | CYP2A6CYP2B6CYP2E1ENPP1CYP3A4 | |
| SCHEMBL7874320 | 0.69 | NQO2 (0.53) | CYP2A6CYP2B6CYP2E1ENPP1CYP3A4 | |
| SCHEMBL30168582 | 0.69 | TDO2 (0.61) | CYP2A6CYP2B6CYP2E1KDRTDO2 | |
| SCHEMBL4946960 | 0.69 | CYP2A6 (0.64) | CYP2A6CYP2B6CYP2E1TDO2CYP3A4 | |
| SCHEMBL20561837 | 0.66 | KDR (0.71) | IMPDH2KDRTDO2CYP3A4CYP2C9 | |
| SCHEMBL5190739 | 0.65 | ALDH1A1 (0.54) | IMPDH2CYP2A6CYP2B6CYP2E1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637301-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-08 | — | — | EP | disclosed |