Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27802263 | 0.89 | LMNA (0.56) | MMP12FFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL7332325 | 0.86 | FFAR1 (0.58) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL10853169 | 0.85 | FFAR1 (0.64) | MMP12FFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL193318 | 0.84 | FFAR1 (0.79) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2862583 | 0.82 | MMP12 (0.68) | MMP12FFAR1LMNAGAAF2RL1 | |
| SCHEMBL1532408 | 0.82 | MMP12 (0.79) | MMP12FFAR1PLAAT5PLAAT4HTT | |
| Hydrochloric Acid SCHEMBL29184696 | 0.82 | FFAR1 (0.76) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| Hydrochloric Acid SCHEMBL28568409 | 0.82 | FFAR1 (0.76) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7508200 | 0.81 | MMP12 (0.66) | MMP12FFAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL755111 | 0.80 | F2RL1 (0.57) | MMP12FFAR1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189851-B2 | Condensed heterocyclic compounds as calcitonin agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-13 | — | — | US | disclosed |
| US-20050107419-A1 | Condensed heterocyclic compounds as calcitonin agonists | SMITHKLINE BEECHAM CORPORATION | 2005-05-19 | — | — | US | disclosed |
| WO-2003076440-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107419-A1 | Condensed heterocyclic compounds as calcitonin agonists | CALCRL, CALCR, CALCB | MMP12 3732/4885FFAR1 664/4885PLAAT3 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.