Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162517 | 0.83 | DRD2 (0.64) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL5117266 | 0.81 | GAA (0.53) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL5114515 | 0.81 | GAA (0.54) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL7094383 | 0.79 | DRD2 (0.47) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL7094166 | 0.78 | DRD2 (0.54) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL29046800 | 0.78 | DRD2 (0.66) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL7094783 | 0.78 | DRD2 (0.59) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL7090542 | 0.78 | GAA (0.58) | GAADRD2DRD3DRD4MAPT | |
| SCHEMBL7534110 | 0.77 | DRD2 (0.65) | GAADRD2DRD3DRD4HTR2A | |
| SCHEMBL5113532 | 0.77 | DRD2 (0.65) | GAADRD2DRD3DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030050307-A1 | Novel indole derivatives | H. LUNDBECK A/S (DK) | 2003-03-13 | — | — | US | claimed |
| US-20030050307-A1 | Novel indole derivatives | H. LUNDBECK A/S (DK) | 2003-03-13 | — | — | US | disclosed |
| EP-1246818-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049680-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050307-A1 | Novel indole derivatives | HTR1A, HTR3C, HTR2C | GAA 4874/4885DRD2 27/4885DRD3 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.