Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093358 | 0.86 | LMNA (0.50) | LMNAALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL7095932 | 0.76 | ALDH1A1 (0.46) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL27579613 | 0.72 | ESR1 (0.56) | ESR1ESR2LMNAALDH1A1MEN1 | |
| SCHEMBL6056000 | 0.71 | TSHR (0.79) | ESR1ESR2LMNAALDH1A1MEN1 | |
| SCHEMBL7095374 | 0.70 | IDO1 (0.42) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29180071 | 0.69 | TSHR (0.44) | LMNAALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL2576783 | 0.68 | ALDH1A1 (0.50) | ESR1ESR2LMNAALDH1A1MEN1 | |
| SCHEMBL28381518 | 0.68 | ESR1 (0.45) | ESR1ESR2LMNAALDH1A1MEN1 | |
| SCHEMBL22310259 | 0.66 | ESR1 (1.00) | ESR1ESR2LMNAALDH1A1MEN1 | |
| SCHEMBL125355 | 0.66 | ESR1 (0.65) | ESR1ESR2LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |