Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095932 | 0.89 | ALDH1A1 (0.46) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL7090779 | 0.86 | ESR1 (0.48) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL7095374 | 0.82 | IDO1 (0.42) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL3447644 | 0.77 | TRPA1 (0.46) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL1275688 | 0.77 | TRPA1 (0.46) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL11321260 | 0.77 | LMNA (0.47) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL29180071 | 0.76 | TSHR (0.44) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL2565087 | 0.73 | TSHR (0.41) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL16793850 | 0.70 | LMNA (0.49) | LMNATSHRTRPA1ALDH1A1POLB | |
| SCHEMBL12138866 | 0.70 | MAOB (0.53) | LMNATSHRTRPA1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |