Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093358 | 0.89 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2TRPA1TSHR | |
| SCHEMBL7095374 | 0.83 | IDO1 (0.42) | ALDH1A1LMNASMN1; SMN2TRPA1TSHR | |
| SCHEMBL7090779 | 0.76 | ESR1 (0.48) | ALDH1A1LMNASMN1; SMN2TRPA1TSHR | |
| SCHEMBL5773518 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2TRPA1HTR2A | |
| SCHEMBL2159670 | 0.70 | HTR2A (0.41) | ALDH1A1LMNASMN1; SMN2HTR2ATDP1 | |
| SCHEMBL1275688 | 0.69 | TRPA1 (0.46) | ALDH1A1LMNASMN1; SMN2TRPA1HTR2A | |
| SCHEMBL3447644 | 0.69 | TRPA1 (0.46) | ALDH1A1LMNASMN1; SMN2TRPA1HTR2A | |
| SCHEMBL13721485 | 0.68 | HTR2A (0.47) | ALDH1A1LMNASMN1; SMN2HTR2AKDM4E | |
| SCHEMBL7093907 | 0.68 | HTR2A (0.56) | ALDH1A1HTR2ATSHRTDP1MAPK1 | |
| SCHEMBL11321260 | 0.68 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |