Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510985 | 0.83 | PDE4B (0.33) | KCNH2 | |
| SCHEMBL7092526 | 0.80 | PTGER4 (0.35) | KCNH2 | |
| SCHEMBL7006178 | 0.63 | CDC7 (0.32) | — | |
| SCHEMBL4142457 | 0.60 | MAPT (0.34) | — | |
| SCHEMBL1751841 | 0.60 | GPR3 (0.32) | — | |
| SCHEMBL5015480 | 0.59 | CA12 (0.39) | — | |
| SCHEMBL3450325 | 0.58 | MAPT (0.32) | — | |
| SCHEMBL29955470 | 0.56 | — | — | |
| SCHEMBL29720280 | 0.56 | KDR (0.34) | — | |
| SCHEMBL16017509 | 0.55 | MTNR1A (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347959-A1 | INDOLE DERIVATIVES AS LIGANDS OF THYROID RECEPTORS | Bayer Aktiengesellschaft (DE) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002051805-A1 | INDOLE DERIVATIVES AS LIGANDS OF THYROID RECEPTORS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |