Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510985 | 0.78 | PDE4B (0.33) | — | |
| SCHEMBL1697462 | 0.77 | PRPS1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7473942 | 0.76 | PRPS1 (0.34) | CDC7PIM1CSNK2BCSNK2A1SLC6A2 | |
| SCHEMBL7481653 | 0.76 | CNR2 (0.39) | — | |
| SCHEMBL7006184 | 0.74 | SLC6A4 (0.36) | CDC7PIM1CSNK2BCSNK2A1SLC6A4 | |
| SCHEMBL7470825 | 0.74 | HTR1A (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6968879 | 0.73 | DYRK1A (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7472995 | 0.72 | HTR6 (0.48) | — | |
| SCHEMBL7478883 | 0.71 | CYP19A1 (0.35) | CSNK2A1 | |
| SCHEMBL1697454 | 0.69 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |
| US-6329390-B1 | BIHETEROCYCLIC INDOLES AS ANALGESICS AND NERVOUS SYSTEM DISORDERS | NPS ALLELIX CORP. (CA) | 2001-12-11 | — | — | US | disclosed |
| EP-1098896-A1 | 5-BICYCLOINDOLE COMPOUNDS | NPS Allelix Corp. (CA) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004019-A1 | 5-BICYCLOINDOLE COMPOUNDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-01-27 | — | — | WO | disclosed |