SCHEMBL709135

SCHEMBL709135

C=CCOCc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.42
ESR2 Q92731 4/20 0.42
IDO1 P14902 2/20 0.42
MGAM O43451 4/20 0.38
GAA P10253 4/20 0.38
SI P14410 4/20 0.38
MGAM2 Q2M2H8 4/20 0.38
MMP3 P08254 1/20 0.37
BCL2L1 Q07817 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ABAT P80404 1/20 0.35
ABL1 P00519 1/20 0.35
ABCB1 P08183 1/20 0.35
BCR P11274 1/20 0.35
ALDH2 P05091 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307672 0.94 IDO1 (0.46) ESR1ESR2IDO1MEN1KMT2A
SCHEMBL472164 0.88 ESR1 (0.50) ESR1ESR2MGAMGAASI
SCHEMBL4778780 0.85 TSHR (0.42) IDO1MEN1KMT2A
SCHEMBL8727939 0.85 ALDH1A1 (0.46) IDO1GAAMEN1KMT2AALDH2
SCHEMBL8730874 0.85 ALDH1A1 (0.46) IDO1GAAMEN1KMT2AALDH2
SCHEMBL8732049 0.83 ALDH1A1 (0.41) IDO1MEN1KMT2A
SCHEMBL8727967 0.83 ALDH1A1 (0.41) IDO1MEN1KMT2A
SCHEMBL11887099 0.81 IDO1 (0.32) IDO1MEN1KMT2A
Hydroquinone SCHEMBL438337 0.81 HSD17B10 (0.42) ESR1ESR2IDO1MGAMGAA
SCHEMBL472120 0.81 MMP3 (0.58) ESR1ESR2IDO1MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945737-B1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEMICAL LTD (KR) 2013-03-06 EP disclosed
US-8123977-B2 Copolymer for liquid crystal alignment, liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2012-02-28 US disclosed
EP-1945737-A1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG Chem, Ltd. (KR) 2008-07-23 EP disclosed
WO-2007052979-A1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEM. LTD. (KR) 2007-05-10 WO disclosed
US-20070102668-A1 Copolymer for liquid crystal alignment , liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2007-05-10 US disclosed
US-20010007880-A1 Material based on crosslinked silicone polymer comprising an immobilized photoinitiator, process for the preparation thereof, hydrophilic polymeric product obtained from this material and process for the preparation thereof, and novel photoinitiators ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2001-07-12 US disclosed
US-6197842-B1 CONTACT LENSES ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2001-03-06 US disclosed