SCHEMBL7307672

SCHEMBL7307672

C=CCOCc1ccc(O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
ESR1 P03372 3/20 0.42
ESR2 Q92731 2/20 0.42
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ABAT P80404 1/20 0.39
APP P05067 1/20 0.38
CA2 P00918 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
SLC6A2 P23975 2/20 0.37
CYP2C19 P33261 2/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
HTR3A P46098 1/20 0.37
BACE1 P56817 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
XDH P47989 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709135 0.94 ESR1 (0.42) IDO1ESR1ESR2KMT2AMEN1
SCHEMBL4778780 0.91 TSHR (0.42) IDO1KMT2AMEN1CA2ALDH1A1
Hydroquinone SCHEMBL438337 0.86 HSD17B10 (0.42) IDO1ESR1ESR2KMT2AMEN1
SCHEMBL16949959 0.83 TSHR (0.36) ALDH1A1TP53TSHR
SCHEMBL5347405 0.82 ESR1 (0.48) IDO1ESR1ESR2KMT2ACA2
SCHEMBL9095391 0.81 AGXT (0.48) IDO1CA2ALDH1A1TAAR1TP53
SCHEMBL4591314 0.81 IDO1 (0.48) IDO1KMT2AMEN1APPALDH1A1
SCHEMBL8758520 0.81 ALDH1A1 (0.46) CA2ALDH1A1TP53TSHRTDP1
SCHEMBL13370317 0.81 TSHR (0.41) KMT2AMEN1APPALDH1A1L3MBTL1
SCHEMBL20953940 0.80 TSHR (0.61) IDO1CA2KDM4EL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8107781-A None JP disclosed
JP-H08107781-A IMPROVER FOR AROMA AND FLAVOR OR TOBACCO T HASEGAWA CO LTD 1996-04-30 JP disclosed
EP-0330036-B1 PROCESS FOR THE PREPARATION OF P-HYDROXY-BENZALDEHYDES BAYER AG (DE) 1990-09-26 EP disclosed
US-4929766-A OXIDATION OF P-CRESOLS WITH CHELATES OF IRON OR MANGANESE BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0330036-A1 Process for the preparation of p-hydroxy-benzaldehydes BAYER AG (DE) 1989-08-30 EP disclosed
US-4804612-A PLASMA DRY-ETCHING RESISTANCE TOKYO OHKA KOGYO CO., LTD. (JP) 1989-02-14 US disclosed
US-4258062-A ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-03-24 US disclosed
US-4171370-A Phenoxy-amino-propanols MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-10-16 US disclosed