Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058170 | 0.84 | CYP11B2 (0.61) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL6285180 | 0.84 | CYP11B2 (0.61) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL31608568 | 0.84 | CYP11B2 (0.65) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL319265 | 0.84 | CYP11B2 (0.65) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL6287169 | 0.82 | CYP11B1 (0.54) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL30487694 | 0.82 | CYP11B1 (0.54) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL31666281 | 0.82 | CYP11B2 (0.62) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL25358298 | 0.81 | CYP11B2 (0.53) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL7090742 | 0.81 | CYP11B1 (0.53) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 | |
| SCHEMBL16516818 | 0.81 | CYP11B2 (0.53) | CYP11B2CYP11B1PTGS2IP6K1IP6K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| CN-1228072-A | Process for preparing 2-aryl-substituted indenes | MONTELL TECHNOLOGY COMPANY BV (NL) | 1999-09-08 | — | — | CN | disclosed |
| EP-0910560-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | Montell Technology Company bv (NL) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998046547-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |