Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575641 | 0.78 | HSPB1 (0.44) | MAPTLMNANPSR1POLBCCR6 | |
| SCHEMBL1024954 | 0.76 | ALDH1A1 (0.47) | LMNAHPGDTDP1L3MBTL1MAPK1 | |
| SCHEMBL29672268 | 0.76 | ALDH1A1 (0.47) | LMNAHPGDTDP1L3MBTL1MAPK1 | |
| SCHEMBL4475384 | 0.76 | LMNA (0.44) | MAPTLMNAHPGDTDP1KDM4E | |
| SCHEMBL9788491 | 0.75 | SERPINE1 (0.56) | LMNAPOLBTDP1MEN1KMT2A | |
| SCHEMBL27886588 | 0.75 | CYP1A2 (0.53) | MAPTLMNAHPGDMEN1KMT2A | |
| SCHEMBL9132620 | 0.74 | TDP1 (0.49) | MAPTLMNANPSR1HPGDTDP1 | |
| SCHEMBL1023324 | 0.73 | ALDH1A1 (0.47) | MAPTLMNAHPGDTDP1MEN1 | |
| SCHEMBL7084529 | 0.73 | SERPINE1 (0.61) | MAPTLMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9127093 | 0.73 | L3MBTL1 (0.64) | MAPTLMNANPSR1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |