SCHEMBL7091485

SCHEMBL7091485

CC1=Cc2ccn(-c3ccccc3)c2C1O[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.33
COMT P21964 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096558 0.77 NOTUM (0.33) NOTUMCOMT
SCHEMBL7096550 0.76 ALDH1A1 (0.34) NOTUM
SCHEMBL7094837 0.72
Hydrochloric Acid SCHEMBL5949045 0.72 NOTUM (0.33) NOTUMCOMT
SCHEMBL7092765 0.65 ALDH1A1 (0.34) NOTUM
SCHEMBL6442527 0.57 NOTUM (0.39) NOTUMCOMT
SCHEMBL1107780 0.55 NOTUM (0.57) NOTUMCOMT
SCHEMBL30763485 0.53 DDB1 (0.48) NOTUMCOMT
SCHEMBL1127502 0.53 ATM (0.48) NOTUMCOMT
SCHEMBL28310215 0.53 SMN1; SMN2 (0.47) NOTUMCOMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1334107-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS Basell Polyolefine GmbH (DE) 2003-08-13 EP disclosed
WO-2002032908-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2002-04-25 WO disclosed