SCHEMBL7092765

SCHEMBL7092765

CC1=Cc2c(cc(C)n2-c2ccccc2)C1O[SiH](C)C

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
NOTUM Q6P988 1/20 0.34
RAB9A P51151 3/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 2/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096550 0.78 ALDH1A1 (0.34) ALDH1A1NOTUMRAB9AKDM4ELMNA
SCHEMBL7094837 0.71
Hydrochloric Acid SCHEMBL5948892 0.70 RAB9A (0.35) ALDH1A1NOTUMRAB9AKDM4ELMNA
SCHEMBL7091485 0.65 NOTUM (0.33) NOTUM
Hydrochloric Acid SCHEMBL6519202 0.63 ALDH1A1 (0.35) ALDH1A1NOTUMRAB9AKDM4ELMNA
SCHEMBL6442563 0.60 ALDH1A1 (0.41) ALDH1A1NOTUMRAB9AKDM4ELMNA
Hydrochloric Acid SCHEMBL6520728 0.59 ALDH1A1 (0.33) ALDH1A1NOTUMRAB9AKDM4ELMNA
SCHEMBL5974667 0.59 ALDH1A1 (0.40) ALDH1A1NOTUMRAB9AKDM4ELMNA
Hydrochloric Acid SCHEMBL1071449 0.58 ALDH1A1 (0.39) ALDH1A1NOTUMRAB9AKDM4ELMNA
Hydrochloric Acid SCHEMBL6515877 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1334107-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS Basell Polyolefine GmbH (DE) 2003-08-13 EP disclosed
WO-2002032908-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2002-04-25 WO disclosed