Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092765 | 0.78 | ALDH1A1 (0.34) | ALDH1A1NOTUMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7091485 | 0.76 | NOTUM (0.33) | NOTUM | |
| SCHEMBL7094837 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL5948948 | 0.70 | RAB9A (0.35) | ALDH1A1NOTUMSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6520728 | 0.62 | ALDH1A1 (0.33) | ALDH1A1NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6446839 | 0.59 | ALDH1A1 (0.40) | ALDH1A1NOTUMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5857932 | 0.57 | ALDH1A1 (0.58) | ALDH1A1NOTUMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9370346 | 0.57 | POLB (0.64) | ALDH1A1NOTUMSMN1; SMN2MAPTKDM4E | |
| SCHEMBL65301 | 0.57 | MAPT (0.54) | ALDH1A1NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6448191 | 0.56 | ALDH1A1 (0.37) | ALDH1A1NOTUMSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |