Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6989619 | 0.99 | PRMT5 (0.50) | PRMT5KDM4EALDH1A1KMT2ADHFR | |
| SCHEMBL6991856 | 0.94 | PRMT5 (0.43) | PRMT5KDM4EALDH1A1KMT2ADHFR | |
| Hydrochloric Acid SCHEMBL6996290 | 0.93 | PRMT5 (0.43) | PRMT5KDM4EALDH1A1KMT2ADHFR | |
| SCHEMBL7001767 | 0.80 | OPRM1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL7003624 | 0.79 | OPRM1 (0.39) | KMT2A | |
| SCHEMBL6988613 | 0.78 | PARP1 (0.58) | PRMT5KDM4EALDH1A1KMT2A | |
| SCHEMBL7091666 | 0.74 | PFKFB3 (0.33) | PFKFB3 | |
| Hydrochloric Acid SCHEMBL6989617 | 0.73 | IDO1 (0.33) | PFKFB3 | |
| SCHEMBL6253383 | 0.72 | KDM4E (0.58) | PRMT5KDM4EALDH1A1KMT2ADHFR | |
| SCHEMBL6999674 | 0.72 | PARP1 (0.60) | PRMT5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |