Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | WRN | Q14191 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3462896 | 0.85 | TSHR (0.45) | TSHRPRKCANAAAALDH1A1CYP1A2 | |
| SCHEMBL7087659 | 0.85 | ALDH1A1 (0.38) | TSHRPRKCAALDH1A1 | |
| SCHEMBL24062145 | 0.82 | TSHR (0.40) | TSHRPRKCANAAAALDH1A1CYP1A2 | |
| SCHEMBL4496230 | 0.79 | PRKCA (0.34) | PRKCANAAAALDH1A1CYP1A2HPGD | |
| SCHEMBL12263773 | 0.74 | TSHR (0.48) | TSHRPRKCA | |
| SCHEMBL25525763 | 0.74 | TSHR (0.45) | TSHRPRKCA | |
| SCHEMBL14563512 | 0.73 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL17208827 | 0.73 | NAAA (0.36) | PRKCANAAAALDH1A1CYP1A2HPGD | |
| SCHEMBL21561626 | 0.72 | PRKCA (0.36) | TSHRPRKCAALDH1A1CYP2C19 | |
| SCHEMBL3462874 | 0.72 | TSHR (0.46) | TSHRPRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653486-B2 | Photopolymerizable; vinyl ether, photoinitiator, iodinium salt, and visible light sensitizer; dentistry, adhesives | CURATORS OF THE UNIVERSITY OF MISSOURI | 2003-11-25 | — | — | US | disclosed |
| US-20030119931-A1 | Novel spiroorthocarbonates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2003-06-26 | — | — | US | disclosed |
| US-6458865-B2 | FOR DENTAL RESTORATION MATERIAL | CURATORS OF THE UNIVERSITY OF MISSOURI | 2002-10-01 | — | — | US | disclosed |
| US-20020013380-A1 | PHOTOPOLYMERIZABLE VINYL ETHER BASED MONOMERIC FORMULATIONS AND POLYMERIZABLE COMPOSITIONS WHICH MAY INCLUDE CERTAIN NOVEL SPIROORTHOCARBONATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-31 | — | — | US | disclosed |