Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20A | O95235 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 3/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726614 | 0.80 | TDO2 (0.49) | TDO2CLK1DYRK1AIDO1GPR84 | |
| SCHEMBL7091761 | 0.77 | TDO2 (0.46) | TDO2CLK1DYRK1AIDO1KCNH2 | |
| SCHEMBL5725721 | 0.77 | GPR84 (0.63) | TDO2CLK1DYRK1AGPR84HTR2A | |
| SCHEMBL3220165 | 0.76 | MPO (0.56) | GPR84HTR2A | |
| SCHEMBL17242222 | 0.74 | HTR2A (0.54) | KCNH2GPR84HTR2AHTR2C | |
| SCHEMBL17242338 | 0.72 | KCNH2 (0.48) | KCNH2GPR84HTR2AHTR2C | |
| SCHEMBL5726248 | 0.72 | TDO2 (0.79) | TDO2CLK1DYRK1A | |
| SCHEMBL19192950 | 0.72 | KIF20A (0.73) | KIF20ACLK1DYRK1AIDO1ALDH1A1 | |
| SCHEMBL5727457 | 0.71 | GPR84 (0.43) | CLK1DYRK1AGPR84HTR2AHTR2C | |
| SCHEMBL9651541 | 0.70 | HTR2A (0.53) | GPR84HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355900-A2 | HETEROCYCLYLALKYLINDOLE OR -AZAINDOLE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002051832-A2 | HETEROCYCLYLALKYLINDOLE OR -AZAINDOLE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2002-07-04 | — | — | WO | disclosed |