Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085823 | 0.76 | POLB (0.50) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL4966437 | 0.74 | POLB (0.54) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL20848220 | 0.74 | POLB (0.54) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL4966443 | 0.74 | POLB (0.54) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL8415734 | 0.72 | KMT2A (0.63) | MAPTTHRBACHEBACE1KMT2A | |
| SCHEMBL13754804 | 0.72 | L3MBTL1 (0.56) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL2680934 | 0.72 | L3MBTL1 (0.56) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL8415735 | 0.72 | KMT2A (0.63) | MAPTTHRBACHEBACE1KMT2A | |
| SCHEMBL13957726 | 0.72 | L3MBTL1 (0.56) | MAPTHPGDTHRBACHEBACE1 | |
| SCHEMBL4893960 | 0.72 | L3MBTL1 (0.56) | MAPTHPGDTHRBACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084662-A2 | COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |