SCHEMBL252040

SCHEMBL252040

C=CCOC(=O)C=Cc1ccc(OC)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
APP P05067 1/20 0.61
GSK3B P49841 1/20 0.59
FLT3 P36888 1/20 0.59
F3 P13726 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
THRB P10828 1/20 0.57
ATM Q13315 1/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MAPT P10636 2/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CASP3 P42574 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
GAA P10253 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5403708 1.00 LMNA (0.62) LMNATDP1APPGSK3BFLT3
Acrylic Acid SCHEMBL2498158 0.94 THRB (0.59) LMNATDP1APPGSK3BFLT3
SCHEMBL5259319 0.86 LMNA (0.63) LMNATDP1GSK3BF3SMN1; SMN2
SCHEMBL14560098 0.85 GSK3B (0.56) LMNATDP1GSK3BFLT3F3
SCHEMBL7092085 0.85 LMNA (0.67) LMNATDP1GSK3BFLT3F3
SCHEMBL11820773 0.84 APP (0.64) LMNAAPPSMN1; SMN2KMT2AMAPT
SCHEMBL9855983 0.84 LMNA (0.68) LMNATDP1GSK3BF3SMN1; SMN2
SCHEMBL9855976 0.84 LMNA (0.68) LMNATDP1GSK3BF3SMN1; SMN2
SCHEMBL8148439 0.84 LMNA (0.68) LMNATDP1GSK3BF3SMN1; SMN2
SCHEMBL11832170 0.83 KMT2A (0.57) LMNATDP1GSK3BF3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107526-B1 TOPICAL ANHYDROUS FILL FORMULATION FOR ULTRAVIOLET FILTERS SCHERER TECHNOLOGIES LLC R P (US) 2020-07-29 EP claimed
EP-2675453-B1 METHODS FOR CONTROLLING PAIN IN CANINES USING A TRANSDERMAL SOLUTION OF FENTANYL ELANCO US INC (US) 2018-08-08 EP claimed
US-20170172895-A1 Topical Anhydrous Fill Formulation For Ultraviolet Filters R.P. SCHERER TECHNOLOGIES, LLC (US) 2017-06-22 US claimed
US-20170128462-A1 METHODS FOR TREATING FEMALE SEXUAL DYSFUNCTION WHILE DECREASING CARDIOVASCULAR RISK ANI PHARMACEUTICALS, INC. 2017-05-11 US claimed
EP-3107526-A1 TOPICAL ANHYDROUS FILL FORMULATION FOR ULTRAVIOLET FILTERS R.P. Scherer Technologies, LLC (US) 2016-12-28 EP claimed
WO-2015126874-A1 TOPICAL ANHYDROUS FILL FORMULATION FOR ULTRAVIOLET FILTERS R.P. SCHERER TECHNOLOGIES, LLC (US) 2015-08-27 WO claimed
EP-2675453-A1 METHODS FOR CONTROLLING PAIN IN CANINES USING A TRANSDERMAL SOLUTION OF FENTANYL ELI LILLY AND CO. (US) 2013-12-25 EP claimed
EP-2675454-A1 METHODS FOR CONTROLLING PAIN IN EQUINES USING A TRANSDERMAL SOLUTION OF FENTANYL ELI LILLY AND CO. (US) 2013-12-25 EP claimed
US-20120322828-A1 METHODS FOR CONTROLLING PAIN IN EQUINES USING A TRANSDERMAL SOLUTION OF FENTANYL ELI LILLY AND COMPANY (US) 2012-12-20 US claimed
WO-2012112355-A1 METHODS FOR CONTROLLING PAIN IN EQUINES USING A TRANSDERMAL SOLUTION OF FENTANYL ELI LILLY AND COMPANY (US) 2012-08-23 WO claimed
US-6299900-B1 NON-OCCLUSIVE, PERCUTANEOUS OR TRANSDERMAL DRUG DELIVERY SYSTEM MONASH UNIVERSITY (AU) 2001-10-09 US claimed
EP-0812309-B1 PROCESS FOR PREPARATION OF CINNAMATE SUNSCREEN AGENTS ISP VAN DYK INC (US) 2000-04-26 EP claimed
EP-0901368-A4 DERMAL PENETRATION ENHANCERS AND DRUG DELIVERY SYSTEMS INVOLVING SAME UNIV MONASH (AU) 2000-01-26 EP claimed
EP-0901368-A1 DERMAL PENETRATION ENHANCERS AND DRUG DELIVERY SYSTEMS INVOLVING SAME MONASH UNIVERSITY (AU) 1999-03-17 EP claimed
EP-0812309-A1 PROCESS FOR PREPARATION OF CINNAMATE SUNSCREEN AGENTS ISP Van Dyk Inc. (US) 1997-12-17 EP claimed
WO-1997029735-A1 DERMAL PENETRATION ENHANCERS AND DRUG DELIVERY SYSTEMS INVOLVING SAME MONASH UNIVERSITY (AU) 1997-08-21 WO claimed
WO-1996019436-A1 PROCESS FOR PREPARATION OF CINNAMATE SUNSCREEN AGENTS ISP VAN DYK INC. (US) 1996-06-27 WO claimed
US-5527947-A Process for preparation of cinnamate sunscreen agents ISP VAN DYK INC. (US) 1996-06-18 US claimed
US-4592906-A Ester of p-dimethylaminocinnamic acid GRAESSER LABORATORIES, LTD. (GB) 1986-06-03 US claimed
EP-0153089-A1 Ultra-violet absorbing compounds and compositions containing said compounds GRAESSER LABORATORIES LIMITED (GB) 1985-08-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120322828-A1 METHODS FOR CONTROLLING PAIN IN EQUINES USING A TRANSDERMAL SOLUTION OF FENTANYL OPRL1, OPRK1, S100P LMNA 3078/4885TDP1 2151/4885APP 2508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.