Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740358 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL5679214 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL7094248 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL7091916 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1POLB | |
| SCHEMBL28518907 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHSP90AA1ERN1 | |
| SCHEMBL16659632 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL10153371 | 0.71 | TSHR (0.38) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL7094845 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EMEN1LMNA | |
| SCHEMBL13590027 | 0.71 | S100B (0.50) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27965052 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084662-A2 | COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |