Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6805667 | 0.99 | FLT3 (0.39) | FLT3KITMEN1LMNAKMT2A | |
| SCHEMBL6801089 | 0.87 | KHK (0.39) | — | |
| SCHEMBL7089406 | 0.84 | ALDH1A1 (0.51) | MEN1LMNAKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL6811362 | 0.83 | CRACR2A (0.39) | — | |
| SCHEMBL6805271 | 0.81 | BDKRB1 (0.38) | LMNA | |
| SCHEMBL7135489 | 0.81 | HDAC1 (0.40) | — | |
| SCHEMBL6801682 | 0.81 | HDAC1 (0.40) | — | |
| SCHEMBL7137097 | 0.80 | KHK (0.44) | LMNAKMT2A | |
| SCHEMBL6805857 | 0.80 | KHK (0.44) | LMNAKMT2A | |
| SCHEMBL6801047 | 0.79 | L3MBTL1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324998-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030923-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-04-18 | — | — | WO | disclosed |