Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.40 |
| ▸ | THRA | P10827 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089760 | 1.00 | THRB (0.40) | THRBTHRAGAAICMTPKM | |
| SCHEMBL13542838 | 0.79 | THRB (0.49) | THRBTHRAICMTCA12CA1 | |
| SCHEMBL7089445 | 0.76 | HDAC3 (0.48) | THRBTHRAICMTCA12CA1 | |
| SCHEMBL7089449 | 0.76 | HDAC3 (0.48) | THRBTHRAICMTCA12CA1 | |
| SCHEMBL7088914 | 0.75 | HSD17B10 (0.43) | HRH3LMNA | |
| SCHEMBL13542841 | 0.74 | HDAC3 (0.44) | THRBTHRAICMTCA12CA1 | |
| SCHEMBL7089006 | 0.73 | HDAC3 (0.45) | THRBTHRAICMTCA12CA1 | |
| SCHEMBL7092305 | 0.73 | FOXO1 (0.46) | THRBTHRAICMTHRH3CA12 | |
| SCHEMBL7092254 | 0.72 | HDAC3 (0.44) | THRBTHRAICMTCA12CA1 | |
| SCHEMBL7089774 | 0.71 | SMN1; SMN2 (0.45) | GAAPKMKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | claimed |