Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093332 | 0.86 | HSD17B10 (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1573105 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1572915 | 0.75 | ALDH1A1 (0.68) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL72613 | 0.71 | AR (0.43) | HPGDLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1573422 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8987259 | 0.69 | TAS2R38 (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL6995912 | 0.68 | BRD4 (0.34) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL6990226 | 0.68 | BRD4 (0.43) | KDM4EMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1573566 | 0.67 | TYMP (0.62) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1573392 | 0.67 | TYMP (0.62) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084935-A2 | DIARYL PYRIMIDINONE DERIVATIVES USEFUL FOR THE TREATMENT OF INFLAMMATION AND IMMUNOGOLICAL DISEASES | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-10-16 | — | — | WO | claimed |
| WO-2003084935-A2 | DIARYL PYRIMIDINONE DERIVATIVES USEFUL FOR THE TREATMENT OF INFLAMMATION AND IMMUNOGOLICAL DISEASES | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-10-16 | — | — | WO | disclosed |