Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 13/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | INMT | O95050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096495 | 0.84 | ALDH1A1 (0.45) | HRH3PTGER4KDM4EMEN1ALDH1A1 | |
| SCHEMBL6645348 | 0.83 | HRH3 (0.47) | HRH3PTGER4HTR1APTGER2MEN1 | |
| SCHEMBL6850945 | 0.76 | HDAC1 (0.44) | HRH3KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6649352 | 0.74 | HRH3 (0.47) | HRH3PTGER4PTGER2KDM4EMEN1 | |
| SCHEMBL988000 | 0.70 | PTGER4 (0.59) | PTGER4PTGER2MAPT | |
| SCHEMBL12495697 | 0.70 | HRH3 (0.43) | HRH3PTGER4HTR1APTGER2MEN1 | |
| SCHEMBL11842202 | 0.69 | HRH3 (0.51) | HRH3HTR1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL19603145 | 0.69 | HRH3 (0.51) | HRH3PTGER4HTR1APTGER2MEN1 | |
| SCHEMBL29977549 | 0.68 | HRH3 (0.50) | HRH3HTR1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL27158593 | 0.68 | HRH3 (0.50) | HRH3HTR1AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173519-B1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL-HEINZ (DE) | 2003-08-20 | — | — | EP | disclosed |