Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.43 |
| ▸ | INMT | O95050 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096495 | 0.91 | ALDH1A1 (0.45) | HRH3ALDH1A1ALOX15GAAMAPT | |
| SCHEMBL6649352 | 0.85 | HRH3 (0.47) | HRH3ALDH1A1MAPTSMN1; SMN2PTGER4 | |
| SCHEMBL7093451 | 0.83 | HRH3 (0.39) | HRH3ALDH1A1MAPTTSHRPTGER4 | |
| SCHEMBL6643060 | 0.80 | NOTUM (0.44) | ALDH1A1ALOX15GAAMAPTTSHR | |
| SCHEMBL12495697 | 0.80 | HRH3 (0.43) | HRH3ALDH1A1ALOX15GAAMAPT | |
| SCHEMBL988000 | 0.80 | PTGER4 (0.59) | GAAMAPTPTGER4PTGER2 | |
| SCHEMBL7326479 | 0.79 | HRH3 (0.43) | HRH3HTR1ACHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL8575078 | 0.78 | CHRM1 (0.44) | HRH3HTR1ACHRM2CHRM4CHRM1 | |
| SCHEMBL19603145 | 0.78 | HRH3 (0.51) | HRH3ALDH1A1PTGER4INMTPTGER2 | |
| SCHEMBL11842202 | 0.78 | HRH3 (0.51) | HRH3ALDH1A1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | HRH3 781/4885ALDH1A1 2174/4885ALOX15 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.