Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495829 | 0.92 | PTGER4 (0.39) | HRH3ALDH1A1PTGER4MAPTPTGER2 | |
| SCHEMBL6645348 | 0.80 | HRH3 (0.47) | HRH3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL7096495 | 0.77 | ALDH1A1 (0.45) | HRH3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL6649352 | 0.74 | HRH3 (0.47) | HRH3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL11842202 | 0.73 | HRH3 (0.51) | HRH3MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29977549 | 0.72 | HRH3 (0.50) | HRH3MEN1KMT2AALDH1A1GAA | |
| SCHEMBL7225028 | 0.72 | CXCR5 (0.45) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27158593 | 0.72 | HRH3 (0.50) | HRH3MEN1KMT2AALDH1A1GAA | |
| SCHEMBL9828733 | 0.71 | HRH3 (0.49) | HRH3MEN1KMT2AALDH1A1PTGER4 | |
| SCHEMBL30487811 | 0.71 | HRH3 (0.49) | HRH3MEN1KMT2AALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | AOC3, AOC2, AOC1 | HRH3 30/4885MEN1 2735/4885KMT2A 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.