Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11784274 | 0.99 | HTR1D (0.57) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| SCHEMBL7087068 | 0.83 | HTR1D (0.45) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| SCHEMBL7035386 | 0.78 | HTR1D (0.58) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| Hydrochloric Acid SCHEMBL11784262 | 0.77 | HTR1D (0.57) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| SCHEMBL7033559 | 0.77 | ALOX15 (0.57) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| Hydrochloric Acid SCHEMBL10353910 | 0.76 | ALOX15 (0.56) | ADRA2AADRA2CADRA2BADRA1AADRA1D | |
| SCHEMBL11788752 | 0.75 | HTR1D (0.48) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| SCHEMBL4760243 | 0.75 | HTR1D (1.00) | HTR1DADRA2AADRA2CADRA2BADRA1A | |
| SCHEMBL18236212 | 0.74 | PIM1 (0.49) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6990259 | 0.73 | NISCH (0.54) | HTR1DLMNACYP2D6NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181730-A1 | Novel benzimidazole derivatives | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181730-A1 | Novel benzimidazole derivatives | OPRD1, OPRL1, OPRM1 | HTR1D 495/4885ADRA2A 123/4885ADRA2C 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.