Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094120 | 0.93 | SLC6A2 (0.41) | SLC6A2SLC6A4CPN1CPB2TAAR1 | |
| SCHEMBL7093914 | 0.83 | TAAR1 (0.52) | SLC6A2SLC6A4TAAR1HTR2ASLC6A3 | |
| SCHEMBL7090263 | 0.82 | CYP3A4 (0.50) | SLC6A2SLC6A4TAAR1HTR2AMAOA | |
| SCHEMBL7093897 | 0.81 | IDO1 (0.46) | SLC6A2SLC6A4TAAR1HTR2A | |
| SCHEMBL7092760 | 0.77 | HTR2A (0.43) | SLC6A2SLC6A4TAAR1HTR2A | |
| SCHEMBL7093907 | 0.74 | HTR2A (0.56) | SLC6A2SLC6A4TAAR1HTR2ASLC6A3 | |
| SCHEMBL7093212 | 0.73 | NR3C1 (0.54) | — | |
| SCHEMBL677579 | 0.73 | MAOA (0.42) | MAOAMAOBCYP3A4CASP1RECQL | |
| SCHEMBL15389542 | 0.71 | CYP3A4 (0.48) | CPN1CPB2TAAR1HTR2AMAOA | |
| SCHEMBL7093888 | 0.70 | CPN1 (0.46) | SLC6A2SLC6A4CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |