Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093914 | 0.89 | TAAR1 (0.52) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7092760 | 0.85 | HTR2A (0.43) | HTR2ATAAR1SLC6A2SLC6A4CHRM2 | |
| SCHEMBL7090263 | 0.84 | CYP3A4 (0.50) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7093897 | 0.83 | IDO1 (0.46) | HTR2ATAAR1SLC6A2SLC6A4CHRM2 | |
| SCHEMBL7094120 | 0.77 | SLC6A2 (0.41) | HTR2ATAAR1SLC6A2SLC6A4CHRNB2 | |
| SCHEMBL7093892 | 0.74 | SLC6A2 (0.45) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9533613 | 0.72 | HTR2A (1.00) | HTR2ATAAR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9528231 | 0.72 | HTR2A (1.00) | HTR2ATAAR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9531164 | 0.72 | HTR2A (1.00) | HTR2ATAAR1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL7094983 | 0.72 | NR3C2 (0.57) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |