Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820638 | 0.83 | FFAR3 (0.35) | GABRR1 | |
| SCHEMBL4460559 | 0.83 | FFAR3 (0.35) | GABRR1 | |
| SCHEMBL2820641 | 0.83 | FFAR3 (0.35) | GABRR1 | |
| Ammonia Solution, Strong SCHEMBL6313571 | 0.79 | FOLH1 (0.30) | GABRR1 | |
| SCHEMBL31531969 | 0.78 | NOS3 (0.33) | GABRR1 | |
| SCHEMBL3515517 | 0.76 | ALDH1A1 (0.32) | GABRR1 | |
| SCHEMBL3515511 | 0.76 | ALDH1A1 (0.32) | GABRR1 | |
| SCHEMBL7266899 | 0.75 | TP53 (0.45) | LMNAALOX15BLMPMP22 | |
| SCHEMBL4822726 | 0.75 | LMNA (0.37) | LMNAALOX15BLMPMP22 | |
| SCHEMBL4799786 | 0.75 | LMNA (0.37) | LMNAALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843663-B9 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NAT RECH SCIENT (FR) | 2003-10-29 | — | — | EP | disclosed |
| EP-0843663-B1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NAT RECH SCIENT (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-0843663-A1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997005113-A1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1997-02-13 | — | — | WO | disclosed |