SCHEMBL7094039

SCHEMBL7094039

O=C(O)c1ccc(-c2cnc(-c3ccc(OCc4ccccc4)cc3)nc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.72
NR4A1 P22736 1/20 0.72
NR4A3 Q92570 1/20 0.72
SRD5A2 P31213 1/20 0.67
PLA2G4B P0C869 1/20 0.63
MAP4K4 O95819 2/20 0.60
PTGES O14684 1/20 0.58
ALOX5 P09917 1/20 0.58
MAOB P27338 1/20 0.56
PARP10 Q53GL7 1/20 0.56
RXRA P19793 3/20 0.55
RXRB P28702 3/20 0.55
NPC1 O15118 1/20 0.55
POLB P06746 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MCL1 Q07820 2/20 0.54
PTPN1 P18031 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8331353 0.90 NR4A2 (0.69) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL4949143 0.90 NR4A2 (0.90) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Hydrochloric Acid SCHEMBL8378883 0.88 NR4A2 (0.87) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL7092038 0.87 LMNA (0.67) NR4A2NR4A1NR4A3SRD5A2MAOB
SCHEMBL5582767 0.85 NR4A2 (0.81) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL1756343 0.85 NR4A2 (0.81) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL6830467 0.85 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL228477 0.85 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL4059143 0.85 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL11603952 0.83 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739884-B1 Liquid crystal compound and liquid crystal composition containing the same SEMICONDUCTOR ENERGY LAB (JP) 2003-08-13 EP disclosed
EP-0821050-B1 Optically active compound and antiferroelectric liquid crystal composition containing the same SEMICONDUCTOR ENERGY LAB (JP) 2001-11-28 EP disclosed
US-5820782-A LOW THRESHOLD VOLTAGE AND LOW VISCOSITY; PYRIMIDINE-BASED COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-10-13 US disclosed
US-5716542-A Liquid crystal compound and liquid crystal composition containing the same TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-02-10 US disclosed
EP-0821050-A1 Optically active compound and antiferroelectric liquid crystal composition containing the same Takasago International Corporation (JP) 1998-01-28 EP disclosed
EP-0739884-A2 Liquid crystal compound and liquid crystal composition containing the same Takasago International Corporation (JP) 1996-10-30 EP disclosed