SCHEMBL709404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL709754	0.80	EPHX2 (0.53)	EPHX2HDAC2HDAC8HDAC6ALDH1A1
	SCHEMBL3821716	0.79	EPHX2 (0.46)	EPHX2HDAC2HDAC8HDAC6BRD4
	SCHEMBL706689	0.78	ALDH1A1 (0.43)	P2RY12ALDH1A1L3MBTL1MEN1KMT2A
	SCHEMBL3824738	0.76	CDK8 (0.49)	EPHX2HDAC2HDAC8HDAC6ALDH1A1
	SCHEMBL705650	0.75	ALDH1A1 (0.43)	P2RY12ALDH1A1L3MBTL1LMNATUBB4A
	SCHEMBL5138385	0.74	HDAC6 (0.73)	EPHX2HDAC2HDAC8HDAC6ALDH1A1
	SCHEMBL31773	0.72	LOXL2 (0.52)	HDAC6ALDH1A1L3MBTL1KDM4ELMNA
	SCHEMBL3823655	0.72	NAMPT (0.43)	HDAC2HDAC8HDAC6L3MBTL1KDM4E
	SCHEMBL3814838	0.72	CACNA1G (0.51)	ALDH1A1HPGDMEN1KMT2AKDM4E
	SCHEMBL20189519	0.71	RAB9A (0.53)	HDAC2HDAC8HDAC6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.