SCHEMBL709406

SCHEMBL709406

O=C1C=CC(=O)N1SN1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 0.42
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
FAAH O00519 7/20 0.38
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
GMNN O75496 1/20 0.36
THPO P40225 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
HSP90AA1 P07900 3/20 0.35
TLR9 Q9NR96 2/20 0.35
PKM P14618 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
XBP1 P17861 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24003668 0.73
SCHEMBL16256331 0.73
SCHEMBL5577325 0.71 MGLL (0.43) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL3795749 0.71 MGLL (0.41) MGLLALDH1A1LMNAMAPTPKM
SCHEMBL19954787 0.69 MGLL (0.35) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL11749637 0.67 ALDH1A1 (0.47) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL19848642 0.67 MGLL (0.39) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL157324 0.65 MGLL (0.50) MGLLGSK3AGSK3BFAAHNPSR1
SCHEMBL1163597 0.64 MGLL (0.50) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL3697751 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4416284-A1 EXTRA-HEPATIC DELIVERY IRNA COMPOSITIONS AND METHODS OF USE THEREOF Alnylam Pharmaceuticals, Inc. (US) 2024-08-21 EP claimed
CN-118176300-A Huntington (HTT) iRNA agent compositions and methods of use thereof 阿尔尼拉姆医药品有限公司 2024-06-11 CN claimed
EP-4353266-A1 LIGAND-BOUND NUCLEIC ACID COMPLEX Rena Therapeutics Inc. (JP) 2024-04-17 EP claimed
WO-2023064530-A1 EXTRA-HEPATIC DELIVERY IRNA COMPOSITIONS AND METHODS OF USE THEREOF ALNYLAM PHARMACEUTICALS, INC. (US) 2023-04-20 WO claimed
US-11059938-B2 Film composition and a film prepared thereby INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2021-07-13 US claimed
EP-3166406-B1 CYTOKINE-CHITOSAN BIOCONJUGATES AND METHODS OF USING THE SAME UNIV ARKANSAS (US) 2020-08-05 EP claimed
US-20200109234-A1 FILM COMPOSITION AND A FILM PREPARED THEREBY INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-04-09 US claimed
US-20170288261-A1 ANODE COMPOSITE MATERIAL, METHOD FOR MAKING THE SAME, AND LITHIUM ION BATTERY JIANGSU HUADONG INSTITUTE OF LI-ION BATTERY CO., LTD. (CN) 2017-10-05 US claimed
US-20170271658-A1 CATHODE COMPOSITE MATERIAL, LITHIUM ION BATTERY, AND METHOD FOR MAKING THE SAME JIANGSU HUADONG INSTITUTE OF LI-ION BATTERY CO., LTD. (CN) 2017-09-21 US claimed
US-20170214048-A1 LITHIUM ION BATTERY JIANGSU HUADONG INSTITUTE OF LI-ION BATTERY CO., LTD. (CN) 2017-07-27 US claimed
US-20080160404-A1 Gel polymer electrolyte precursor and rechargeable cell comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-07-03 US claimed
US-20080160418-A1 NONAQUEOUS ELECTROLYTE HAVING MALEIMIDE ADDITIVES AND SECONDARY CELLS EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-07-03 US claimed
US-20070141461-A1 High ionic conductivity gel polymer electrolyte for rechargeble polymber secondary battery INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2007-06-21 US claimed
CN-1964127-A High ionic conductivity colloidal polymer electrolyte for chargeable and dischargeable polymer secondary battery IND TECH RES INST (CN) 2007-05-16 CN claimed
US-20040077021-A1 Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes ROCHE DIAGNOSTICS CORPORATION 2004-04-22 US claimed
US-20030175995-A1 Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes ROCHE DIAGNOSTICS OPERATIONS, INC. 2003-09-18 US claimed
US-20030170917-A1 Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes ROCHE DIAGNOSTICS CORPORATION 2003-09-11 US claimed
EP-1340980-A1 Derivatives of amphetamine, antibodies against said derivatives, reagent kits, methods of producing said antibodies, and methods of detecting said derivatives Roche Diagnostics GmbH (DE) 2003-09-03 EP claimed
EP-1340981-A2 Antibodies for detecting amphetamine derivatives Roche Diagnostics GmbH (DE) 2003-09-03 EP claimed
US-4004627-A Pneumatic tire with sidewall composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-01-25 US claimed