SCHEMBL7094366

SCHEMBL7094366

CCCCCCCC[C@H](C(=O)NCC)N(O)C=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
TRPA1 O75762 1/20 0.40
DDAH1 O94760 1/20 0.40
GAPDH P04406 1/20 0.40
FAAH O00519 2/20 0.40
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
RRM1 P23921 1/20 0.36
TLL1 O43897 1/20 0.35
BMP1 P13497 1/20 0.35
MMP12 P39900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098147 0.81 EPHX1 (0.41) DPP7EPHX1
SCHEMBL28601020 0.72 CA2 (0.52) MAPTFAAHGNAI3GNAO1GNAI1
SCHEMBL26030776 0.72 CA2 (0.52) MAPTFAAHGNAI3GNAO1GNAI1
SCHEMBL21250702 0.72 CA2 (0.52) MAPTFAAHGNAI3GNAO1GNAI1
SCHEMBL8431170 0.72 CA2 (0.52) MAPTFAAHGNAI3GNAO1GNAI1
SCHEMBL18612532 0.72 CA2 (0.52) MAPTFAAHGNAI3GNAO1GNAI1
SCHEMBL17360824 0.71 TSHR (0.36) FAAHPPARG
SCHEMBL9298988 0.71 GPR84 (0.59) MAPTTRPA1DDAH1GAPDHFAAH
SCHEMBL4773839 0.71 CTSK (0.40)
SCHEMBL29204741 0.70 ZDHHC20 (0.44) MAPTTRPA1DDAH1GAPDHFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815084-B1 LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE PROCTER & GAMBLE (US) 2003-08-27 EP claimed
EP-0815084-B1 LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE PROCTER & GAMBLE (US) 2003-08-27 EP disclosed
EP-0815084-A1 LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE THE PROCTER & GAMBLE COMPANY (US) 1998-01-07 EP disclosed
WO-1996029313-A1 LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE THE PROCTER & GAMBLE COMPANY (US) 1996-09-26 WO disclosed