Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 12/20 | 0.57 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864324 | 1.00 | HTR2C (0.58) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL7094448 | 1.00 | HTR2C (0.58) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL25058901 | 0.83 | HTR2C (0.59) | HTR2CHTR2AHTR2BKDM1ATAAR1 | |
| SCHEMBL1643784 | 0.79 | KDM1A (0.47) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL1643791 | 0.79 | KDM1A (0.47) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL5004304 | 0.79 | KDM1A (0.47) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL3841365 | 0.79 | KDM1A (0.47) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL1643782 | 0.79 | KDM1A (0.47) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL15064669 | 0.77 | HTR2C (0.45) | HTR2CHTR2AHTR2BKDM1AMAOB | |
| SCHEMBL807474 | 0.77 | HTR2C (0.45) | HTR2CHTR2AHTR2BKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829456-B2 | Halogen substituted diketones, pyrazole compounds and processes for the manufacture of pyrazole compounds | SOLVAY SA (BE) | 2020-11-10 | — | — | US | disclosed |
| US-20190276409-A1 | PROCESS FOR THE MANUFACTURE OF CARBOXYLIC ACIDS OR CARBOXYLIC ACID DERIVATIVES | SOLVAY SA (BE) | 2019-09-12 | — | — | US | disclosed |
| US-20190031616-A1 | HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | SOLVAY SA (BE) | 2019-01-31 | — | — | US | disclosed |
| US-20190031617-A1 | PROCESS FOR THE MANUFACTURE OF CARBOXAMIDES | SOLVAY SA (BE) | 2019-01-31 | — | — | US | disclosed |
| CN-108779096-A | A kind of fluorine-substituted cyclopropylamine class compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2018-11-09 | — | — | CN | disclosed |
| CN-107200706-A | Cyclopropylamine class compound of one class fluorine substitution and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2017-09-26 | — | — | CN | disclosed |
| WO-2017140593-A1 | PROCESS FOR THE MANUFACTURE OF CARBOXAMIDES | SOLVAY SA (BE) | 2017-08-24 | — | — | WO | disclosed |
| US-20170217901-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY SA (BE) | 2017-08-03 | — | — | US | disclosed |
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031617-A1 | PROCESS FOR THE MANUFACTURE OF CARBOXAMIDES | AADAC, PC, CPS1 | HTR2C 1095/4885HTR2A 1981/4885HTR2B 1546/4885 |
| US-20190276409-A1 | PROCESS FOR THE MANUFACTURE OF CARBOXYLIC ACIDS OR CARBOXYLIC ACID DERIVATIVES | CBX2, RCC2, PRXL2A | HTR2C 2068/4885HTR2A 2098/4885HTR2B 2337/4885 |
| US-20170217901-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | HRH4, IL4I1, HRH3 | HTR2C 725/4885HTR2A 2880/4885HTR2B 1326/4885 |
| US-10829456-B2 | Halogen substituted diketones, pyrazole compounds and processes for the manufacture of pyrazole compounds | CYP3A4, PDXK, CYP3A43 | HTR2C 2215/4885HTR2A 3584/4885HTR2B 3310/4885 |
| US-20190031616-A1 | HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | CYP3A4, PDXK, CYP3A43 | HTR2C 2215/4885HTR2A 3584/4885HTR2B 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.