SCHEMBL7095115

SCHEMBL7095115

C=C=[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218232 0.79 HTR2A (0.35) HTR6HTR2A
SCHEMBL7947949 0.76 HTR6 (0.39) HTR6HTR2A
SCHEMBL3380394 0.76 HTR2A (0.35) HTR6HTR2A
SCHEMBL15334106 0.75 HTR6 (0.33) HTR6HTR2A
SCHEMBL28978370 0.75 HTR6 (0.33) HTR6HTR2A
SCHEMBL30577433 0.74 HTR2A (0.40) HTR6HTR2A
SCHEMBL2763485 0.73 SIGMAR1 (0.35) HTR6HTR2A
SCHEMBL3385286 0.73 HTR6 (0.33) HTR6HTR2A
SCHEMBL7184249 0.73 HTR2A (0.33) HTR6HTR2A
SCHEMBL3385865 0.72 HTR2A (0.35) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0515132-B2 Olefin polymerization catalyst and olefin polymerization MITSUI CHEMICALS INC (JP) 2003-08-27 EP disclosed
EP-0515132-B1 Olefin polymerization catalyst and olefin polymerization MITSUI CHEMICALS INC (JP) 1998-08-12 EP disclosed
US-5296565-A Polymerizing olefins using catalyst comprising particulate oxide carrier, organoaluminum oxy compound, metallocene, organoaluminum compound, prepolymerized polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-22 US disclosed
US-5252529-A Coordination catalyst using a moisture-adsorbed carrier of a metal oxide; addition polymers having excellent melt tension and moldability and broad molecular weight distribution MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-12 US disclosed
EP-0515132-A2 Olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-11-25 EP disclosed