Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6860914 | 0.99 | NAAA (0.35) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL5853894 | 0.81 | EPHX2 (0.41) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5853318 | 0.81 | EPHX2 (0.41) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5853352 | 0.81 | POLB (0.38) | ALDH1A1HTTHPGD | |
| Hydrochloric Acid SCHEMBL6842057 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5853425 | 0.78 | ALOX5 (0.37) | ALDH1A1HTTHPGD | |
| Hydrochloric Acid SCHEMBL5855359 | 0.78 | ALDH1A1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5853536 | 0.76 | MAPK1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5852722 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5853650 | 0.72 | SMN1; SMN2 (0.33) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |