Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | ERN1 | O75460 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607733 | 0.91 | GABRA1 (0.64) | GABRA1GABRB2ERN1ALDH1A1TSHR | |
| SCHEMBL1527079 | 0.91 | GABRA1 (0.64) | GABRA1GABRB2ERN1ALDH1A1TSHR | |
| SCHEMBL29957719 | 0.87 | ERN1 (0.61) | GABRA1GABRB2ERN1ALDH1A1TSHR | |
| SCHEMBL172956 | 0.87 | ERN1 (0.61) | GABRA1GABRB2ERN1ALDH1A1TSHR | |
| SCHEMBL20339223 | 0.85 | ERN1 (0.59) | GABRA1GABRB2ERN1ALDH1A1TSHR | |
| SCHEMBL31229333 | 0.81 | GABRA1 (0.73) | GABRA1GABRB2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL263474 | 0.81 | GABRA1 (0.73) | GABRA1GABRB2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9824952 | 0.79 | GABRA1 (0.77) | GABRA1GABRB2ALDH1A1PTGER1PTGER4 | |
| SCHEMBL29953931 | 0.79 | ERN1 (0.52) | GABRA1GABRB2ERN1TLR2TLR1 | |
| Orthocresol SCHEMBL11559977 | 0.79 | ERN1 (0.62) | ERN1ALDH1A1TSHRTLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |