Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.53 |
| ▸ | F9 | P00740 | 3/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812427 | 0.82 | CYP3A4 (0.48) | MAOBF9F10BCHEALDH1A1 | |
| SCHEMBL6807206 | 0.82 | MAOB (0.48) | MAOBF9F10BCHEALDH1A1 | |
| SCHEMBL7105405 | 0.80 | MAOB (0.50) | L3MBTL1MAOBITGA4NAPEPLDF9 | |
| SCHEMBL7101117 | 0.80 | L3MBTL1 (0.50) | L3MBTL1ITGA4NAPEPLDHCRTR1PAX8 | |
| SCHEMBL8377008 | 0.80 | TUBB4A (0.61) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6812016 | 0.80 | MAOB (0.48) | L3MBTL1MAOBF9F10BCHE | |
| SCHEMBL7744153 | 0.80 | MAOB (0.48) | L3MBTL1MAOBF9F10BCHE | |
| SCHEMBL9405631 | 0.78 | MAOB (0.71) | MAOBF9F10ERN1BCHE | |
| Hydrochloric Acid SCHEMBL7097572 | 0.78 | ESR1 (0.64) | ITGA4NAPEPLD | |
| SCHEMBL7100621 | 0.77 | L3MBTL1 (0.46) | L3MBTL1ITGA4NAPEPLDHCRTR1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838461-B1 | Substituted 2,3-aryl-benzothiophene compounds having estrogenic activity | LILLY CO ELI (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6121293-A | SUCH AS 2-(4-METHOXYPHENYL)-3-(3-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)-6 -METHOXYBENZO(B)THIOPHENE HYDROCHLORIDE; FOR TREATING OSTEOPOROSIS, HYPERLIPIDEMIA, AND ESTROGEN-DEPENDENT CANCER | ELI LILLY AND COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| US-5843940-A | Benzothiophene compounds, compositions, and method | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0838461-A2 | Substituted 2,3-aryl-benzothiophene compounds having estrogenic activity | ELI LILLY AND COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |