Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.48 |
| ▸ | TUBB | P07437 | 3/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10170739 | 0.87 | HSP90AA1 (0.57) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7096339 | 0.80 | L3MBTL1 (0.57) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8640626 | 0.80 | HSP90AA1 (0.50) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8158106 | 0.77 | TUBB4A (0.72) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7100621 | 0.77 | L3MBTL1 (0.46) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16346487 | 0.74 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1026075 | 0.74 | HSD17B1 (0.68) | ESR1APPNPC1TP53MAPK1 | |
| SCHEMBL6976023 | 0.73 | TUBB4A (0.56) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL7097572 | 0.73 | ESR1 (0.64) | ITGA4NAPEPLDESR1ESR2 | |
| SCHEMBL8643567 | 0.73 | TUBB4A (0.58) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838461-B1 | Substituted 2,3-aryl-benzothiophene compounds having estrogenic activity | LILLY CO ELI (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6121293-A | SUCH AS 2-(4-METHOXYPHENYL)-3-(3-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)-6 -METHOXYBENZO(B)THIOPHENE HYDROCHLORIDE; FOR TREATING OSTEOPOROSIS, HYPERLIPIDEMIA, AND ESTROGEN-DEPENDENT CANCER | ELI LILLY AND COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| US-5843940-A | Benzothiophene compounds, compositions, and method | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0838461-A2 | Substituted 2,3-aryl-benzothiophene compounds having estrogenic activity | ELI LILLY AND COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |