Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | F9 | P00740 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812016 | 0.95 | MAOB (0.48) | CYP3A4MAOBNPSR1MAPTF9 | |
| SCHEMBL6806171 | 0.91 | CYP3A4 (0.53) | CYP3A4MAOBNPSR1MAPTF9 | |
| SCHEMBL6808221 | 0.88 | CYP3A4 (0.48) | CYP3A4MAOBMAPTF9F10 | |
| SCHEMBL6807721 | 0.88 | CYP3A4 (0.48) | CYP3A4MAOBMAPTF9F10 | |
| SCHEMBL6807206 | 0.86 | MAOB (0.48) | CYP3A4MAOBNPSR1MAPTF9 | |
| SCHEMBL6812421 | 0.83 | TUBB4A (0.57) | CYP3A4NPSR1MAPTALDH1A1HTT | |
| SCHEMBL7096339 | 0.82 | L3MBTL1 (0.57) | MAOBNPSR1F9F10ALDH1A1 | |
| SCHEMBL8377008 | 0.81 | TUBB4A (0.61) | MAOBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20442802 | 0.81 | ESR1 (0.57) | MGAMGAASIMGAM2TUBB4A | |
| SCHEMBL7744153 | 0.81 | MAOB (0.48) | MAOBNPSR1F9F10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | CONRAD PRESTON CHARLES (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | TPST2, SULT1A1, TYR | CYP3A4 45/4885MAOB 70/4885NPSR1 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.