Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7091936 | 0.90 | TPSAB1 (0.48) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| Formic Acid SCHEMBL7236466 | 0.90 | ADRB3 (0.49) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| Formic Acid SCHEMBL7097100 | 0.89 | ADRB3 (0.55) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| Formic Acid SCHEMBL7094920 | 0.88 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| Formic Acid SCHEMBL7095538 | 0.88 | NAMPT (0.43) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| SCHEMBL7091755 | 0.86 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| SCHEMBL7091709 | 0.84 | ADRB3 (0.59) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| Formic Acid SCHEMBL7091593 | 0.82 | ADRB3 (0.58) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| SCHEMBL7092224 | 0.81 | ADRB3 (0.51) | TPSAB1TPSD1TPSG1ADRB3ADRB1 | |
| Formic Acid SCHEMBL7096055 | 0.81 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | TPSAB1 596/4885TPSD1 651/4885TPSG1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.