Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7237981 | 0.90 | ADRB3 (0.60) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7095348 | 0.89 | ADRB3 (0.61) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7096436 | 0.89 | TPSAB1 (0.46) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7091936 | 0.89 | TPSAB1 (0.48) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7094920 | 0.86 | TPSAB1 (0.47) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7235795 | 0.85 | ADRB3 (0.61) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7097277 | 0.85 | ADRB3 (0.61) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7095538 | 0.85 | NAMPT (0.43) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7091709 | 0.82 | ADRB3 (0.59) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7095573 | 0.81 | ADRB3 (0.62) | ADRB3ADRB1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | ADRB3 3/4885ADRB1 2/4885TPSAB1 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.