Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709149 | 0.93 | HTT (0.38) | HTTHIF1AARPOLBLMNA | |
| SCHEMBL27028806 | 0.88 | POLB (0.41) | HTTADRB2ADRB1ADRB3POLB | |
| SCHEMBL709814 | 0.81 | HTT (0.36) | HTTHIF1AARPOLBLMNA | |
| SCHEMBL346943 | 0.81 | POLB (0.42) | HTTPOLBLMNAMAPTACACB | |
| SCHEMBL31152429 | 0.81 | POLB (0.42) | HTTPOLBLMNAMAPTACACB | |
| SCHEMBL15349 | 0.81 | HTT (0.53) | HTTHIF1AARPOLBLMNA | |
| SCHEMBL20610370 | 0.81 | HTT (0.53) | HTTHIF1AARPOLBLMNA | |
| SCHEMBL22020008 | 0.81 | HTT (0.53) | HTTHIF1AARPOLBLMNA | |
| SCHEMBL11967041 | 0.81 | HTT (0.53) | HTTHIF1AARPOLBLMNA | |
| SCHEMBL14173202 | 0.81 | HTT (0.53) | HTTHIF1AARPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4331559-A1 | DENTAL FILLING KIT | Kuraray Noritake Dental Inc. (JP) | 2024-03-06 | — | — | EP | disclosed |
| US-20220142754-A1 | DENTAL MILL BLANK | KURARAY NORITAKE DENTAL INC. (JP) | 2022-05-12 | — | — | US | disclosed |
| EP-3925593-A1 | DENTAL MILL BLANK | Kuraray Noritake Dental Inc. (JP) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020166667-A1 | DENTAL MILL BLANK | クラレノリタケデンタル株式会社 | 2020-08-20 | — | — | WO | disclosed |
| EP-2119425-B1 | DENTAL COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2019-06-12 | — | — | EP | disclosed |
| EP-3108868-B1 | DENTAL RESTORATIVE COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2018-10-31 | — | — | EP | disclosed |
| US-9993394-B2 | Dental restorative composition | KURARAY NORITAKE DENTAL INC. (JP) | 2018-06-12 | — | — | US | disclosed |
| EP-2275076-B1 | DENTAL COMPOSITION AND COMPOSITE RESIN | KURARAY NORITAKE DENTAL INC (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20170049665-A1 | DENTAL RESTORATIVE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2017-02-23 | — | — | US | disclosed |
| EP-3108868-A1 | DENTAL RESTORATIVE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2016-12-28 | — | — | EP | disclosed |
| EP-2554154-B1 | DENTAL ADHESIVE MATERIAL KIT | KURARAY NORITAKE DENTAL INC (JP) | 2015-10-21 | — | — | EP | disclosed |
| US-8703840-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2014-04-22 | — | — | US | disclosed |
| US-8455564-B2 | Dental composition and composite resin | KURARAY NORITAKE DENTAL INC. (JP) | 2013-06-04 | — | — | US | disclosed |
| EP-2554154-A1 | DENTAL ADHESIVE MATERIAL KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-20120202913-A1 | DENTAL ADHESIVE MATERIAL KIT | KURARAY MEDICAL INC. (JP) | 2012-08-09 | — | — | US | disclosed |
| US-8124669-B2 | Dental composition | KURARAY MEDICAL INC. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | KURARAY MEDICAL INC. (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2275076-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | Kuraray Medical Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20110003267-A1 | DENTAL COMPOSITION | KURARAY MEDICAL INC. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2119425-A1 | DENTAL COMPOSITION | Kuraray Medical Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049665-A1 | DENTAL RESTORATIVE COMPOSITION | CAD, DHCR24, PRNP | HTT 864/4885HIF1A 2479/4885ADRB2 4076/4885 |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | CAD, KATNAL2, ZYX | HTT 1173/4885HIF1A 801/4885ADRB2 3990/4885 |
| US-20110003267-A1 | DENTAL COMPOSITION | NLRP3, TAS2R42, CAD | HTT 704/4885HIF1A 136/4885ADRB2 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.