SCHEMBL346943

SCHEMBL346943

C=C(C)C(=O)OCCOc1ccc(C(C)(C)c2ccc(OC(=O)C(=C)C)c(OCC)c2OCC)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.42
HTT P42858 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
APEX1 P27695 1/20 0.42
THRB P10828 1/20 0.37
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 5/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 2/20 0.33
ACACB O00763 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31152429 1.00 POLB (0.42) POLBHTTTDP1APEX1THRB
SCHEMBL27028806 0.94 POLB (0.41) POLBHTTTDP1APEX1THRB
SCHEMBL32674612 0.92 POLB (0.38) POLBHTTTDP1APEX1THRB
SCHEMBL32674611 0.91 THRB (0.43) POLBHTTTDP1APEX1THRB
SCHEMBL709149 0.86 HTT (0.38) POLBHTTTDP1APEX1KDM4E
SCHEMBL203765 0.85 THRB (0.43) POLBHTTTDP1APEX1THRB
SCHEMBL29415623 0.84 CYP1A2 (0.35) HTTTDP1THRBKDM4EALDH1A1
SCHEMBL64707 0.84 CYP1A2 (0.35) HTTTDP1THRBKDM4EALDH1A1
SCHEMBL32674609 0.82 THRB (0.46) POLBHTTTHRBKDM4EALDH1A1
SCHEMBL3823778 0.82 NPSR1 (0.32) HTTKDM4EMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-20240199494-A1 ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF Kuraray Noritake Dental lnc. (JP) 2024-06-20 US disclosed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US disclosed
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME KURARAY NORITAKE DENTAL INC. (JP) 2024-05-23 US disclosed
WO-2024096102-A1 ZIRCONIA PRE-SINTERED BODY, COMPOSITION, AND METHODS FOR PRODUCING SAME クラレノリタケデンタル株式会社 2024-05-10 WO disclosed
WO-2024096019-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-05-10 WO disclosed
EP-4360609-A1 DENTAL ADHESIVE KIT Kuraray Noritake Dental Inc. (JP) 2024-05-01 EP disclosed
US-20240091107-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-21 US disclosed
US-20240074946-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-07 US disclosed
US-5739177-A PRETREATING AGENT WHICH DECALCIFIES TOOTH SURFACE AND PROMOTES BONDING STRENGTH OF ADHESIVE TO BOTH ENAMEL AND DENTIN TOKUYAMA CORPORATION (JP) 1998-04-14 US disclosed
EP-0811368-A1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORPORATION (JP) 1997-12-10 EP disclosed
EP-0712622-A1 Dental composition and kit TOKUYAMA CORPORATION (JP) 1996-05-22 EP disclosed
EP-0661034-A1 Dental composition TOKUYAMA CORPORATION (JP) 1995-07-05 EP disclosed
US-5260476-A Dental restoration TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5171763-A A dental composite of a monomer containing poly(3,4-carboxylic benzoic acid and acrylic ester moities, an ion leachable filler and an initiator; high adhesion and strength; discoloration inhibition TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
US-4460760-A ADHESIVES OKURA KOGYO KABUSHIKI KAISHA (JP) 1984-07-17 US disclosed
US-4394494-A DIURETHANE TETRAACRYLATES AS POLYMERIZABLE MONOMERS LION CORPORATION (JP) 1983-07-19 US disclosed
US-4388421-A PRIMERS LION CORPORATION (JP) 1983-06-14 US disclosed
US-4383052-A 1-Methacryloxyethane-1,1-diphosphonic acid and its salts and dental adhesive composition containing same LION CORPORATION (JP) 1983-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074946-A1 DENTAL COMPOSITION PIEZO1, TAS2R42, EIF2B3 POLB 589/4885HTT 1523/4885TDP1 3083/4885
US-20240091107-A1 DENTAL COMPOSITION CCT7, TAS2R42, CCT5 POLB 684/4885HTT 1491/4885TDP1 1516/4885
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL POLB 2634/4885HTT 1613/4885TDP1 3589/4885
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME MSL1, ITGA1, ASH2L POLB 4304/4885HTT 4028/4885TDP1 2204/4885
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 POLB 1327/4885HTT 1831/4885TDP1 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.