Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100315 | 0.90 | ABCG2 (0.64) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL7100046 | 0.89 | AR (0.72) | NFE2L2CYP1A1CYP1A2CYP2D6MAOB | |
| SCHEMBL1764951 | 0.89 | NFE2L2 (0.70) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL27794061 | 0.88 | NFE2L2 (0.58) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL4864045 | 0.88 | NFE2L2 (0.72) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL1261537 | 0.87 | NFE2L2 (0.60) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL1261543 | 0.87 | NFE2L2 (0.60) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL5084423 | 0.85 | MAOB (0.80) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL5084427 | 0.85 | MAOB (0.80) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL27794060 | 0.85 | NFE2L2 (0.60) | NFE2L2ALOX5CYP1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |