SCHEMBL7096864

SCHEMBL7096864

N[C@H](Cc1c[nH]c2cc(F)ccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
TSHR P16473 3/20 0.66
KDM4E B2RXH2 3/20 0.66
LMNA P02545 3/20 0.66
MAPT P10636 3/20 0.66
BLM P54132 3/20 0.66
PMP22 Q01453 3/20 0.66
MEN1 O00255 3/20 0.66
HIF1A Q16665 2/20 0.66
MPO P05164 2/20 0.66
PTPRA P18433 1/20 0.65
CYP2C19 P33261 1/20 0.62
HTR2A P28223 4/20 0.61
HTR2C P28335 2/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
NFKB1 P19838 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
HSD17B10 Q99714 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248870 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL18029199 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL2330930 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL30381733 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL120340 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL4262937 0.89 HTR2A (0.60) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL4262934 0.89 HTR2A (0.60) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL125000 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL29623154 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL29358068 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US claimed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO claimed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO claimed
US-20250042961-A1 P53 PEPTIDOMIMETIC MACROCYCLES AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH (SG) 2025-02-06 US claimed
US-20240350681-A1 RADIOLABELED MELANOCORTIN 1 RECEPTOR-SPECIFIC ALPHA-MELANOCYTE-STIMULATING HORMONE ANALOGUES FOR IMAGING OR THERAPY PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2024-10-24 US claimed
CN-118829648-A P53 peptidomimetic macrocycles 默沙东有限责任公司 2024-10-22 CN claimed
EP-4444740-A2 P53 PEPTIDOMIMETIC MACROCYCLES Merck Sharp & Dohme LLC (US) 2024-10-16 EP claimed
US-11992537-B2 Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2024-05-28 US claimed
WO-2023107353-A2 P53 PEPTIDOMIMETIC MACROCYCLES MERCK SHARP & DOHME LLC (US) 2023-06-15 WO claimed
CN-108315370-A A kind of preparation method of halogen tryptophan 滨海吉尔多肽有限公司 2018-07-24 CN claimed
EP-0021585-B1 TRUNCATED SOMATOSTATIN ANALOGS AND INTERMEDIATES THEREFOR, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE ANALOGS AMERICAN HOME PRODUCTS CORPORATION (US) 1983-01-19 EP claimed
EP-0021585-A1 Truncated somatostatin analogs and intermediates therefor, processes for their preparation, and pharmaceutical compositions containing the analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-07 EP claimed
US-4225472-A Truncated somatostatin analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1980-09-30 US claimed
CN-122074077-A Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte stimulating hormone analogs for imaging or therapy 省卫生服务机构 2026-05-22 CN disclosed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US disclosed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
EP-0021585-A1 Truncated somatostatin analogs and intermediates therefor, processes for their preparation, and pharmaceutical compositions containing the analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-07 EP disclosed
EP-0021585-A1 Truncated somatostatin analogs and intermediates therefor, processes for their preparation, and pharmaceutical compositions containing the analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-07 EP disclosed
US-4225472-A Truncated somatostatin analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1980-09-30 US disclosed
US-4225472-A Truncated somatostatin analogs AMERICAN HOME PRODUCTS CORPORATION (US) 1980-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992537-B2 Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy MC1R, MC5R, MC3R KMT2A 1625/4885TSHR 65/4885KDM4E 4278/4885
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof SSTR2, SSTR4, SSTR5 KMT2A 1730/4885TSHR 16/4885KDM4E 3869/4885
US-20240350681-A1 RADIOLABELED MELANOCORTIN 1 RECEPTOR-SPECIFIC ALPHA-MELANOCYTE-STIMULATING HORMONE ANALOGUES FOR IMAGING OR THERAPY MC1R, MC3R, MC5R KMT2A 1737/4885TSHR 81/4885KDM4E 4233/4885
US-20250042961-A1 P53 PEPTIDOMIMETIC MACROCYCLES TP53, MDM2, MDM4 KMT2A 4593/4885TSHR 2072/4885KDM4E 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.